Adeline was born and raised in Singapore, and originally came to the Kline lab to complete her undergraduate Final Year Project in 2012. Adeline stayed in the lab as a research assistant after graduation, and in 2014 she entered the PhD program. She is interested in molecular microbiology and to understand how these microorganisms interacts with each other in the environment. Adeline loves travelling around the world to experience different culture and local delicacies. In her free time, she would spend time doing her favorite sports, which includes running, cycling and racket sports and solving puzzles. Adeline loves food and can recommend the best cafes to you!
Adeline’s project aims to understand factors involved in focal virulence factor assembly in Enterococcus faecalis. Her work focuses on how E. faecalis monitors efficient pilus assembly. She has identified a novel two-component system involved in this process.
Adeline is also involved in several collaborative projects in the lab. She works with Kishore to test novel antimicrobial compounds against several antibiotic resistant pathogens in wound infections. She is also involved in collaboration work to identify virulence factors involved in Candida urinary tract infections.
|1.||Enterococcus faecalis modulates immune activation and slows healing during wound infection.
Chong KKL, Tay WH, Janela B, Yong MHA, Liew TH, Madden L, Keogh D, Barkham T, Ginhoux F, Becker D, Kline KA.; BioRxiv (2017)
|2.||Model systems for the study of Enterococcal colonization and infection. Goh HMS, Yong MHA, Chong KKL, Kline KA.; Virulence (2017)|