Paul Subha Sankar

Paul Subha Sankar

PhD, Yong Lu Lin School of Medicine, National University of Singapore
Advisor: A/P Tan Yee Joo

Paul’s doctoral dissertation (2013-2018) examined the interaction of monoclonal antibodies with the Influenza A virus hemagglutinin protein, as well as engineering of monoclonal antibodies against the H5 and H7 influenza virus hemagglutinin. Paul focused on viral protein engineering, viral protein expression in bacteria and purification, monoclonal antibody expression, purification and characterization and manipulation of antibody affinity through random mutagenesis and phage display panning techniques. As a postdoc in the Kline lab, Paul is focussed on understanding the role of HtrA in the virulence of Enterococcus faecalis and Streptococcus pneumonia. Outside lab, Paul enjoys photography and reading thriller novels.

1. The study of viability of Vibrio cholerae strains in low ionic strength aquatic environment; Subha Sankar Paul, Dr. Eizo Takahashi, Dr. Goutam Chowdhury, Dr. SHIN-ICHI MIYOSHI, Asish K Mukhopadhyay, Dr. Shanta Dutta, Prof. Keinosuke Okamoto; Preprints (2019)
2. Simultaneous o-cresol degradation and biosurfactant production by indigenous bacterial monoculture: kinetics and genotoxic risk assessment; Minati Behera, Indrani Paul,Subha Sankar Paul, Tamal Mandal and Dalia Dasgupta Mandal; Desalination and water treatment (2019)
3. The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis; Zheng Zhiqiang, Subha Sankar Paul, Xiaobing Mo, Yu-Ren Yuan, and Yee-Joo Tan; Vaccines (2018)
4. A cross-clade H5N1 influenza A virus neutralizing monoclonal antibody binds to a novel epitope within the vestigial esterase domain of hemagglutinin; Subha Sankar Paul, Chee-Keng Mok, Tze-Minn Mak, Oi-Wing Ng, James Odame Aboagye, Teddy John Wohlbold, Florian Krammer, Yee-Joo Tan; Antiviral Research (2017)