Irina Afonina

Irina Afonina

PhD, Nanyang Technological University
Irina [at] smart.mit.edu
Irina

Irina was born and raised in Russia, where she completed her undergraduate studies with an engineering degree in biotechnology. Before moving to Singapore, she spent a few years at the Pasteur Institute in St. Petersburg working with resistant bacteria and developing new diagnostic methods. In Singapore, she completed her PhD in the Kline lab addressing the enterococcal adhesins in biofilm formation. After her PhD, Irina joined Singapore-MIT Alliance for Research and Technology under the supervision of Tim Lu and Kimberly Kline to work on combinatorial genetics in Enterococcus faecalis to combat biofilm-associated infections. Outside of the lab, Irina juggles taking care of 2 daughters and a cat, yoga classes, reading, and planning the holidays she hopes to find time for!

1. The composition and function of Enterococcus faecalis membrane vesicles, Afonina I, Tien B, Nair Z, Matysik A, Lam LN, Veleba M, Jie AKJ, Rashid R, Cazenave-Gassiot A, Wenk M, Wai SN, Kline KA; microLife (2021)
2. Multiplex CRISPRi system enables the study of stage-specific biofilm genetic requirements in Enterococcus faecalis. Afonina I, Ong J, Chua J, Lu T, Kline KA; mBio (2020)
3. Planktonic Interference and Biofilm Alliance between Aggregation Substance and Endocarditis- and Biofilm-Associated Pili in Enterococcus faecalis. Afonina I, Lim XN, Tan R, Kline KA; J Bacteriol (2018)
4. Right Place, Right Time: Focalization of Membrane Proteins in Gram-Positive Bacteria. Mitra SD, Afonina I, Kline KA; Trends Microbiol (2016)