Soukayna Jabli
B.Sc. Applied Biology
Masters Student
Soukayna.Jabli [at] etu.unige.ch
https://orcid.org/0009-0004-1257-9977Soukayna Jabli obtained her Bachelor’s degree in Applied Biology in 2019. Following that, she pursued a Master’s in Medical Biotechnology at the Faculty of Medicine and Pharmacy in Rabat, Morocco.
In 2022, she joined the University of Geneva for additional studies in sciences, where she completed a monograph on the molecular basis and biological functions of m6A RNA modifications. In 2023, she began a second Master’s in Molecular Biosciences, Genetics, Development and Evolution at the University of Geneva. In her first year, she completed a three-month internship in Dr. K. Perron’s laboratory at the Microbiology Unit, focusing on identifying targets of the IrlRS two-component system involved in heavy metal resistance in Pseudomonas aeruginosa. In September 2024, she joined the Kline lab to work on her Master’s project, studying lipoteichoic acid synthases in Enterococcus faecalis. In her free time, she enjoys cooking, watching series, and spending time with friends.
Enterococcus faecalis possesses a two-component system, YCIRK, which remains poorly understood. This system is thought to regulate two putative lipoteichoic acid synthases, LtaS1 and LtaS2, as well as two hypothetical genes located in close proximity to the system. To investigate their roles, we will generate deletion mutants, ∆ltaS1 and ∆ltaS2, and assess lipoteichoic acid production via western blot analysis to confirm their function as synthases. Additionally, we will examine LtaS1 and LtaS2’s involvement in modulating various cell envelope properties, such as surface hydrophobicity, surface charge, biofilm formation, and sensitivity to environmental stresses and antibiotics.
