🇨🇭 Brenda Silva Rosa Da Luz

Brenda Silva Rosa Da Luz 

PhD, Institut Agro Rennes-Angers-INRAe
Research fellow
Brenda.Silvarosadaluz [at] unige.ch

Brenda is from Belo Horizonte, Brazil. She graduated in Biological Sciences from the Federal University of Minas Gerais (UFMG), Brazil, and completed during this time several internships, including an exchange program of 18 months at Griffith University, Australia. There, she investigated the influence of the phase variable DNA methyltransferase ModD in the gene regulation of Neisseria meningitidis.

After her bachelor’s degree, Brenda did a Master’s program in Molecular Genetics of Microorganisms at UFMG. Her  project aimed at the identification of genes involved in the adaptation to environmental stresses in the pathogen Corynebacterium pseudotuberculosis.

In 2022, she finished her PhD, which was conducted under an international cotutelle agreement between UFMG and the Institut Agro Rennes-Angers-INRAe, France. This co-supervision project included a 2-year stay in France, which was supported by scholarships granted by CAPES/COFECUB (Brazil) and Campus France. The thesis’ project aimed at the characterization and study of Staphylococcus aureus extracellular vesicles and their impact on the host immune response.

In 2023, Brenda joined the Kline Lab to work with Enterococcus faecalis adaptation in single and multi-species biofilms. In her free time, Brenda loves to cook, travel and explore nature.

1. Impact of Environmental Conditions on the Protein Content of Staphylococcus aureus and Its Derived Extracellular Vesicles. da Luz BSR, Rodovalho VR, Nicolas A, Chabelskaya S, Jardin J, Briard-Bion V, Le Loir Y, Azevedo VAC, Guédon E. Microorganisms. 2022
2. Extracellular Vesicles and Their Role in Staphylococcus aureus Resistance and Virulence. da Luz BSR, Azevedo, VAC; Le-loir, Y ; Guedon, E. In: Dr. Amjad Islam Aqib. (Org.). Book Chapter in Staphylococcus aureus. 1ed.:, 2021
3. Environmental Plasticity of the RNA Content of Staphylococcus aureus Extracellular Vesicles. da Luz BSR, Nicolas A, Chabelskaya S, Rodovalho VR, Le Loir Y, Azevedo VAC, Felden B, Guédon E. Frontiers in Microbiology. 2021
4. Extracellular vesicles produced by human and animal Staphylococcus aureus strains share a highly conserved core proteome. Tartaglia NR, Nicolas A, Rodovalho VR, da Luz BSR, Briard-Bion V, Krupova Z, Thierry A, Coste F, Burel A, Martin P, Jardin J, Azevedo V, Le Loir Y, Guédon E. Scientific Reports. 2020
5. Promoter activity of sigma factor coding genes of Corynebacterium pseudotuberculosis in response to abiotic stresses. da Luz, BSR, Seyffert, N., Profeta, R., Rodrigues, L.G., Brenig, B., Gala-Garcia, A., Diniz, A.B., Meyer, R., de Carvalho Pacheco, L.G., de Menezes, G.B. and Azevedo, V. Gene Reports. 2021
6. Extracellular Vesicles Produced by the Probiotic Propionibacterium freudenreichii CIRM-BIA 129 Mitigate Inflammation by Modulating the NF-κB Pathway. Rodovalho VR, da Luz BSR, Rabah H, do Carmo FLR, Folador EL, Nicolas A, Jardin J, Briard-Bion V, Blottière H, Lapaque N, Jan G, Le Loir Y, de Carvalho Azevedo VA, Guédon E. Frontiers in Microbiology. 2020
7. Environmental conditions modulate the protein content and immunomodulatory activity of extracellular vesicles produced by the probiotic Propionibacterium freudenreichii. de Rezende Rodovalho V, da Luz BSR, Nicolas A, do Carmo FLR, Jardin J, Briard-Bion V, Jan G, Le Loir Y, de Carvalho Azevedo VA, Guedon E. Applied Environmental Microbiology. 2020
8. The polyanions heparin and suramin impede binding of free adenine to a DNA glycosylase from Corynebacterium pseudotuberculosis. Eberle RJ, Coronado MA, Peinado RS, de Moraes FR, Olivier D, Dreyer T, de Oliveira Lopes D, da Luz BSR, Azevedo V, Arni RK. International Journal of Biological Macromolecules. 2019